The Cornell Biological Field Station (CBFS) serves as a primary field site for aquatic research at Cornell University (more information can be found at http://www.dnr.cornell.edu/fieldst/cbfs.htm) and is part of the Department of Natural Resources, College of Agriculture and Life Sciences. The centerpiece of the station's research program is a 50-year database on the food web of Oneida Lake, New York, that has been collected with support from the Cornell University Brown Endowment and from the New York State Department of Environmental Conservation. The data are collected by personnel from the Cornell Biological Field Station and include limnology, benthos, zooplankton, phytoplankton, and fish survey data, primarily from Oneida Lake and spanning 1957 to the present. This data package includes three tables. The first is a summary of limnological data gathered during standard sampling of Oneida Lake from 1975 - 2006. The second provides profile data by depth for temperature, dissolved oxygen, pH, and conductivity. A supplemental table provides the coordinates of the six sampling sites. This program is currently ongoing.